[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"$fYyKOQ2TskzTh8K9KCcz7MYKjWawIb-Bw74p17tiMGaI":3},{"locale":4,"topic":5,"relatedTrends":79},"fr",{"topic":6,"slug":7,"canonicalSlug":8,"topicAliases":9,"nicheKey":12,"nicheName":13,"nicheNameEn":14,"nicheIcon":15,"country":16,"countries":17,"agentKey":18,"score":19,"type":20,"isFresh":21,"isPublic":21,"detectedAt":22,"sources":23,"evidence":76},"Anti-inflammatory treatment targeting immune system for depression","anti-inflammatory-rheumatoid-arthritis-drug-easing-hard-to-treat-depression","anti-inflammatory-treatment-targeting-immune-system-for-depression",[10,11],"Anti-inflammatory drug repurposed to treat hard-to-treat depression","anti-inflammatory rheumatoid arthritis drug easing hard-to-treat depression","sante","Santé & Médecine","Health & Medicine","🏥","US",[16],"sante-US",100,"spiking",false,"2026-05-31T01:23:18.710Z",[24,30,36,41,46,51,56,61,66,71],{"title":25,"url":26,"domain":27,"snippet":28,"content":29},"New depression treatment targets the immune system instead of the brain","https:\u002F\u002Fwww.sciencedaily.com\u002Freleases\u002F2026\u002F05\u002F260527023204.htm","sciencedaily.com","A small trial found that an anti-inflammatory drug used for rheumatoid arthritis eased symptoms in people with treatment-resistant depression while reducing fatigue and anxiety.","Science News\n\nfrom research organizations\n\n* * *\n\nDate:May 28, 2026 Source:University of Bristol Summary:A surprising new approach to depression treatment is showing early promise — not by targeting brain chemicals, but by calming the immune system. In a small clinical trial, researchers found that an anti-inflammatory drug normally used for rheumatoid arthritis appeared to ease symptoms in people with hard-to-treat depression, while also reducing fatigue and anxiety and improving quality of life.Share:\n\nFULL STORY\n\n* * *\n\n!\n\nScientists may have uncovered a completely new way to treat depression — by targeting inflammation instead of the brain alone. Credit: Shutterstock\n\nImmunotherapy may offer a completely new way to treat people with difficult-to-treat depression, according to a University of Bristol-led clinical trial published in _JAMA Psychiatry_ on May 20.\n\nIn the small pilot study, researchers tested whether tocilizumab, a drug commonly prescribed for inflammatory conditions such as rheumatoid arthritis, could ease depression symptoms in patients who had not improved with standard antidepressants.\n\nAlthough the trial included only 30 participants with moderate-to-severe depression, the findings suggest the drug may help reduce depression severity, anxiety, and fatigue while improving quality \n\n[Content truncated...]",{"title":31,"url":32,"domain":33,"snippet":34,"content":35},"A Common Arthritis Drug Appears to Work When Antidepressants Don't","https:\u002F\u002Fwww.sciencealert.com\u002Fa-common-arthritis-drug-appears-to-work-when-antidepressants-dont","sciencealert.com","Around a third of people with major depressive disorder don't respond to standard treatments – but an alternative therapy may be hiding right under our...",null,{"title":37,"url":38,"domain":39,"snippet":40,"content":35},"A Drug Used for Arthritis May Help Treat Depression","https:\u002F\u002Fwww.technologynetworks.com\u002Fneuroscience\u002Fnews\u002Fa-drug-used-for-arthritis-may-help-treat-depression-413067","technologynetworks.com","Researchers investigated, for the first time, whether tocilizumab, an existing anti-inflammatory drug commonly used to treat immune conditions such as...",{"title":42,"url":43,"domain":44,"snippet":45,"content":35},"Clinical trial suggests an anti-inflammatory drug could relieve difficult-to-treat depression","https:\u002F\u002Fwww.psypost.org\u002Fclinical-trial-suggests-an-anti-inflammatory-drug-could-relieve-difficult-to-treat-depression\u002F","psypost.org","A recent clinical trial suggests that treating the immune system with an anti-inflammatory drug could relieve symptoms in people with difficult-to-treat...",{"title":47,"url":48,"domain":49,"snippet":50,"content":35},"Inflammation, not just brain chemistry, holds key to depression relief, says study","https:\u002F\u002Fwww.moneycontrol.com\u002Fhealth-and-fitness\u002Finflammation-not-just-brain-chemistry-holds-key-to-depression-relief-says-study-article-13935390.html","moneycontrol.com","A study has found that an anti-inflammatory drug, normally used for rheumatoid arthritis, may help ease symptoms of treatment-resistant depression.",{"title":52,"url":53,"domain":54,"snippet":55,"content":35},"Anti Inflammatory Market Size, Share, Growth | CAGR of 8.3%","https:\u002F\u002Fmedia.market.us\u002Fglobal-anti-inflammatory-market-news\u002F","media.market.us","Global Anti Inflammatory Market size is expected to be worth around US$ 217.7 Billion by 2034, from US$ 122.4 Billion in 2024.",{"title":57,"url":58,"domain":59,"snippet":60,"content":35},"New depression therapy shifts focus from brain to immune system | Study also used immunosuppressive Tocilizumab | Inshorts","https:\u002F\u002Finshorts.com\u002Fen\u002Famp_news\u002Fnew-depression-therapy-shifts-focus-from-brain-to-immune-system--1779989436302","inshorts.com","Scientists at the University of Bristol identified a new way to treat depression by targeting the immune system instead of brain chemicals.",{"title":62,"url":63,"domain":64,"snippet":65,"content":35},"Trazodone for Dogs: Uses, Side Effects, and Alternatives","https:\u002F\u002Fwww.akc.org\u002Fexpert-advice\u002Fhealth\u002Ftrazodone-for-dogs\u002F","akc.org","Trazodone (brand name Desyrel, Oleptro) is a medication used to treat depression in people. Trazodone is a human medication, but it has several uses in...",{"title":67,"url":68,"domain":69,"snippet":70,"content":35},"Top 10 drugs that may contribute to sexual dysfunction","https:\u002F\u002Fwww.mdlinx.com\u002Farticle\u002Ftop-10-drugs-that-may-contribute-to-sexual-dysfunction\u002F2DX8oKKfmLtyUxNsrSy6kn","mdlinx.com","Sexual function is multiphasic and involves sexual desire, arousal, and orgasm. Men and women can experience issues at any phase, with presentations...",{"title":72,"url":73,"domain":74,"snippet":75,"content":35},"We Tested Some of the Best CBD for Pain Management in 2026","https:\u002F\u002Fwww.medicalnewstoday.com\u002Farticles\u002Fbest-cbd-for-pain-management","medicalnewstoday.com","A vast range of CBD products, including oils, tinctures, and balms, may help people experiencing physical pain.",{"mentionsLast7Days":77,"mentionsLast30Days":77,"firstSeen":22,"lastSeen":22,"relatedEntities":78},7,[26,43,38,73],[80,83,86,89,92,95],{"topic":81,"slug":82,"score":19,"type":20,"country":16,"nicheIcon":15},"trimming damaged meniscus (arthroscopic partial meniscectomy) offers no benefit","trimming-damaged-meniscus-arthroscopic-partial-meniscectomy-offers-no-benefit",{"topic":84,"slug":85,"score":19,"type":20,"country":16,"nicheIcon":15},"Rapid advancement of AI in medical imaging market and adoption drivers","rapid-advancement-of-ai-in-medical-imaging-market-and-adoption-drivers",{"topic":87,"slug":88,"score":19,"type":20,"country":16,"nicheIcon":15},"Mayo Clinic nonprofit medical centers and healthcare services","mayo-clinic-nonprofit-medical-centers-and-healthcare-services",{"topic":90,"slug":91,"score":19,"type":20,"country":16,"nicheIcon":15},"Clinical trial care and outcomes after glioblastoma diagnosis","clinical-trial-care-and-outcomes-after-glioblastoma-diagnosis",{"topic":93,"slug":94,"score":19,"type":20,"country":16,"nicheIcon":15},"Biotechnology applications in medicine, agriculture, and environmental sciences","biotechnology-applications-in-medicine-agriculture-and-environmental-sciences",{"topic":96,"slug":97,"score":19,"type":20,"country":16,"nicheIcon":15},"North America AI in healthcare market projected growth to 2035","north-america-ai-in-healthcare-market-projected-growth-to-2035"]